Basic Information
| LncRNA/CircRNA Name | ASAP1-IT1 |
| Synonyms | ASAP1-IT1, ASAP1-IT, ASAP1IT, ASAP1IT1, DDEF1IT1, HSPC054, NCRNA00050 |
| Region | NA |
| Ensemble | NA |
| Refseq | NR_002765 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Western blot |
| Sample | bladder cancer tissues, cell lines (T24, J82, UMUC3, RT4 and 5637) |
| Expression Pattern | up-regulated |
| Function Description | In our study, we found that an uncharacterized lncRNA, ASAP1-IT1, was overexpressed in UBC tissues compared with adjacent non-malignant tissues. High ASAP1-IT1 expression levels in UBC specimens were correlated with advanced tumor stage, higher clinical stage, poor pathological differentiation and bad overall survival. |
| Pubmed ID | 28895409 |
| Year | 2017 |
| Title | Long noncoding RNA ASAP1-IT1 promotes cancer stemness and predicts a poor prognosis in patients with bladder cancer |
External Links
| Links for ASAP1-IT1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |