Basic Information
| LncRNA/CircRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | RT-PCR, Western blot |
| Sample | NSCLC cell line |
| Expression Pattern | up-regulated |
| Function Description | Compared with normal lung epithelial cells BE-AS-2B, NCI-H838 cells had a significantly increased level of lncRNA-ATB.lncRNA-ATB promotes the apoptosis of NSCLC cells through inhibiting the expression of miR-200a and reversely promoting the expression of ?-catenin. |
| Pubmed ID | 31983095 |
| Year | 2019 |
| Title | LncRNA-ATB promotes apoptosis of non-small cell lung cancer cells through miR-200a/?-Catenin |
External Links
| Links for lncRNA-ATB | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |