Basic Information
| LncRNA/CircRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR |
| Sample | renal cell carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression level of lncRNA-ATB was significantly upregulated in RCC tissues vs. corresponding non-tumor tissues (p<0.01) and the high expression of lncRNA-ATB was significantly associated with histological grade (p=0.008), lymph nodes metastasis (p=0.015), and distant metastasis (p=0.008). Also, Kaplan-Meier analysis indicated patients with high lncRNA-ATB expression that had a significantly shorter overall survival than those with low lncRNA-ATB expression (p<0.001). |
| Pubmed ID | 28682434 |
| Year | 2017 |
| Title | High expression of long non-coding RNA ATB is associated with poor prognosis in patients with renal cell carcinoma |
External Links
| Links for lncRNA-ATB | GenBank HGNC NONCODE |
| Links for renal cell carcinoma | OMIM COSMIC |