Basic Information
| LncRNA/CircRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR etc. |
| Sample | pancreatic cancer tissues, cell lines (HPDE6c-7) |
| Expression Pattern | down-regulated |
| Function Description | We found that lncRNA-ATB expression was decreased in pancreatic cancer tissues and pancreatic cancer cell lines. Low lncRNA-ATB expression levels were significantly correlated with lymph node metastases, neural invasion, and clinical stage. Moreover, patients with low lncRNA-ATB expression levels exhibited markedly worse overall survival prognoses. Multivariate analysis indicated that decreased lncRNA-ATB expression was an independent predictor of poor prognosis in pancreatic cancer patients. |
| Pubmed ID | 26482611 |
| Year | 2015 |
| Title | Downregulation of lncRNA-ATB correlates with clinical progression and unfavorable prognosis in pancreatic cancer |
External Links
| Links for lncRNA-ATB | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |