Basic Information
| LncRNA/CircRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi etc. |
| Sample | cell line (HepG2??CF7??VECs), gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | In gastric tissue samples,cancerous tissues had relatively lower lncRNA-ATB expression levels than noncancerous ones, although the difference was not statistically significant.lncRNA-ATB levels were inversely associated with depth of invasion (T). Trastuzumab resistance and invasion-metastasis cascade in breast cancer is mediated by sponging role of lncRNA-ATB for miR-200c and thus increasing ZEB1 and ZNF- |
| Pubmed ID | 29657927 |
| Year | 2018 |
| Title | Gene Expression Analysis of Two Epithelial-mesenchymal Transition-related Genes: Long Noncoding RNA-ATB and SETD8 in Gastric Cancer Tissues. |
External Links
| Links for lncRNA-ATB | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |