Basic Information
| LncRNA/CircRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi |
| Sample | gastric cancer tissues, cell lines (MGC803, MKN45, BGC823, MKN28 and SGC7901,GES1) |
| Expression Pattern | up-regulated |
| Function Description | higher expression of lncRNA-ATB was correlated with increased invasion depth, more distant metastasis and advanced tumor, node, metastasis stage. downregulated lncRNA-ATB expression suppressed cellular proliferation, invasion and migration of GC cells. Survival analysis also indicated the inverse relationship between lncRNA ATB expression and cancer prognosis. |
| Pubmed ID | 29257203 |
| Year | 2017 |
| Title | Long noncoding RNA-ATB promotes cell proliferation, migration and invasion in gastric cancer |
External Links
| Links for lncRNA-ATB | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |