Basic Information
| LncRNA/CircRNA Name | lncRNA-BCAT1 |
| Synonyms | AK091631 |
| Region | GRCh38_12:24810022-24949459 |
| Ensemble | ENSG00000060982 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot etc. |
| Sample | colorectal cancer tissues, cell lines (HCT-116, SW480, SW620, LoVo, SW1116 and HT29) |
| Expression Pattern | down-regulated |
| Function Description | lncRNA-BCAT1 expression was decreased in CRC tissues, and was negatively associated with B-catenin in both CRC tissues and cell lines. |
| Pubmed ID | 28416735 |
| Year | 2017 |
| Title | Reciprocal control of lncRNA-BCAT1 and B-catenin pathway reveals lncRNA-BCAT1 long non-coding RNA acts as a tumor suppressor in colorectal cancer |
External Links
| Links for lncRNA-BCAT1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |