Basic Information
| LncRNA/CircRNA Name | lncRNA-DQ786227 |
| Synonyms | NA |
| Region | GRCh38_1:12507262-12507643 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR, RNAi, in vitro knockdown etc. |
| Sample | cell lines (A549, QG56 etc.) |
| Expression Pattern | up-regulated |
| Function Description | Expression of lncRNA-DQ786227 in both lung cancer cells differed from that in BEAS-2B cells. Expression of lncRNA-DQ786227 was significantly higher in the A549 and QG56 cells compared with the BEAS-2B cells. Our findings revealed that lncRNA-DQ786227 might act as an oncogene. Our study provides a new insight regarding the oncogenic properties of lncRNA in B[a]P-induced cell transformation. |
| Pubmed ID | 24084393 |
| Year | 2013 |
| Title | LncRNA-DQ786227-mediated cell malignant transformation induced by benzo(a)pyrene. |
External Links
| Links for lncRNA-DQ786227 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |