Basic Information
| LncRNA/CircRNA Name | lncRNA-HEIH |
| Synonyms | HEIH, HCCAT2, LINC-HEIH, LINC00848, lncRNA-HEIH |
| Region | GRCh38_5:180829954-180831605 |
| Ensemble | ENSG00000278970 |
| Refseq | NR_045680 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | exosome | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR, RIP, RNA pull-down assay etc. |
| Sample | HCC tissues, cell lines (Huh7, HepG2) |
| Expression Pattern | up-regulated |
| Function Description | The transcript levels of lncRNA-HEIH were higher in HCC tissues when compared with the corresponding non-tumor liver tissues from the same donor. And we found that patients with high lncRNA-HEIH expression in HCC had significantly worse prognosis than those with low lncRNA-HEIH expression. |
| Pubmed ID | 21769904 |
| Year | 2011 |
| Title | Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. |
External Links
| Links for lncRNA-HEIH | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |