Basic Information
| LncRNA/CircRNA Name | lncRNA-LET |
| Synonyms | NPTN-IT1, lncRNA-LET |
| Region | GRCh38_15:73567012-73569294 |
| Ensemble | ENSG00000281183 |
| Refseq | NR_103844 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR etc. |
| Sample | cervical cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | The results showed that lncRNA LET expression in cervical cancer tissues was significantly down-regulated compared with the adjacent non-tumor tissues. Decreased lncRNA LET expression was significantly correlated with FIGO stage, lymph node metastasis, and depth of cervical invasion, but not other clinical characteristics. |
| Pubmed ID | 25755778 |
| Year | 2015 |
| Title | Low expression of long non-coding RNA LET inhibits carcinogenesis of cervical cancer. |
External Links
| Links for lncRNA-LET | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |