Basic Information
| LncRNA/CircRNA Name | lncUSMycN |
| Synonyms | NA |
| Region | GRCh38_2:15920399-15936017 |
| Ensemble | ENSG00000223850 |
| Refseq | NR_125783 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, Wound healing assay, in vitro knockdown etc. |
| Sample | breast tumors and their adjacent non-tumor tissues,human breast cancer cell lines(ZR-75-1, MCF-7 , and MDA-MB-231) |
| Expression Pattern | up-regulated |
| Function Description | The data showed the significant up-regulation of lncUSMycN in tumor tissues compared to non-tumor specimens. Receiver operating characteristic (ROC) curve analysis demonstrated the biomarker potential of lncUSMycN for invasive breast ductal carcinoma. Furthermore, lncUSMycN knockdown induced apoptosis and suppressed cellular migration in breast cancer cells. |
| Pubmed ID | 31102367 |
| Year | 2019 |
| Title | Clinical and in Vitro Study of Novel Long Non-Coding RNA lncUSMycN in Breast Cancer |
External Links
| Links for lncUSMycN | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |