Basic Information
| LncRNA/CircRNA Name | LOC101928963 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot, Dual Luciferase Reporter Gene Assay |
| Sample | spinal cord tissue,astrocytoma cells (U87R-DOX, FS-001-0642) |
| Expression Pattern | up-regulated |
| Function Description | Decreased cell apoptosis and PMAIP1 expression, as well as overexpressed LOC101928963, were exhibited among spinal cord glioma tissues. LOC101928963 overexpression was observed to promote cell proliferation and cell-cycle entry and inhibit the process of apoptosis. PMAIP1, a target of LOC101928963, displayed a downregulated level following the elevation of LOC101928963. |
| Pubmed ID | 31670198 |
| Year | 2019 |
| Title | Silencing lncRNA LOC101928963 Inhibits Proliferation and Promotes Apoptosis in Spinal Cord Glioma Cells by Binding to PMAIP1 |
External Links
| Links for LOC101928963 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |