Basic Information
| LncRNA/CircRNA Name | LOC283070 |
| Synonyms | CAMK1D, CKLiK, CaM-K1, CaMKID |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR, RNAi, Western blot, Flow cytometry assay, MTT assay etc. |
| Sample | cell lines (LNCaP, PC-3 and DU145) |
| Expression Pattern | up-regulated |
| Function Description | LOC283070 was up-regulated in LNCaP-AI cells and frequently up-regulated in AIPC cell lines. Overexpression of LOC283070 in LNCaP cells accelerated cell proliferation and migration, even under androgen-independent circumstances. Knockdown of LOC283070 inhibited LNCaP-AI cell proliferation and migration. |
| Pubmed ID | 28077997 |
| Year | 2016 |
| Title | Long non-coding RNA LOC283070 mediates the transition of LNCaP cells into androgen-independent cells possibly via CAMK1D. |
External Links
| Links for LOC283070 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |