Basic Information
| LncRNA/CircRNA Name | ASlnc02525 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Luciferase reporter experiment, qPCR etc. |
| Sample | cell lines (HepG2, QGY-7701, SMMC-7721, L-02) |
| Expression Pattern | up-regulated |
| Function Description | ASLNC02525, as an RNA sponge, broke the negative regulation of twist1 by hsa-miRNA-489-3p, and once ASLNC02525 was silenced, the highly expressed hsa-miRNA-489-3p regained its regulation on twist1 and inhibited the proliferation and invasion. |
| Pubmed ID | 28713968 |
| Year | 2017 |
| Title | Inhibition of proliferation and invasion of hepatocellular carcinoma cells by lncRNA-ASLNC02525 silencing and the mechanism. |
External Links
| Links for ASlnc02525 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |