Basic Information
| LncRNA/CircRNA Name | LOC285758 |
| Synonyms | NA |
| Region | GRCh38_6:113868013-113873351 |
| Ensemble | ENSG00000227502 |
| Refseq | NR_038863 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR, Western blot |
| Sample | Bone marrow of acutemyeloid leukemia, cell lines (KG-1a, THP-1) |
| Expression Pattern | up-regulated |
| Function Description | Our results showed that the proliferation of those two cell lines were inhibited after knock-down of LOC285758. enhancer lncRNA LOC285758 showed thesignificant association with the poor overall survival based on 197AML samples from TCGA. |
| Pubmed ID | 28203711 |
| Year | 2017 |
| Title | Genome-wide characterization of lncRNAs in acutemyeloid leukemia |
External Links
| Links for LOC285758 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |