Basic Information
LncRNA/CircRNA Name | LOC441204 |
Synonyms | NA |
Region | GRCh38_7:26486668-26496367 |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | glioma |
ICD-0-3 | NA |
Methods | qPCR, RIP etc. |
Sample | brain tumor tissue, cell lines (U87MG and T98) |
Expression Pattern | up-regulated |
Function Description | LOC441204, a novel non-coding RNA gene displaying high expression in clinical specimens of brain tumor and significant upregulation in glioma cell lines. a pro-oncogenic role of LOC441204 in tumor cell growth through activation of the B-catenin/p21/cdk4 cascade to act as a potential diagnostic marker or therapeutic target in brain tumor. |
Pubmed ID | 28717243 |
Year | 2017 |
Title | The long non-coding RNA LOC441204 enhances cell growth in human glioma. |
External Links
Links for LOC441204 | GenBank HGNC NONCODE |
Links for glioma | OMIM COSMIC |