Basic Information
| LncRNA/CircRNA Name | LOC553103 |
| Synonyms | MIR3936HG, SLC22A5-AS1 |
| Region | GRCh38_5:132311285-132369916 |
| Ensemble | ENSG00000233006 |
| Refseq | NR_110997 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | Microarray, qPCR, RNAi, Luciferase reporter assay etc. |
| Sample | cell line (AGS) |
| Expression Pattern | up-regulated |
| Function Description | We identified and validated that a novel long non-coding RNA (lncRNA) LOC553103 was downregulated by EBV-miR-BART6-3p, and LOC553103 knockdown by specific siRNAs phenocopied the effect of EBV-miR-BART6-3p, while LOC553103 overexpression promoted cancer cell migration and invasion to facilitate EMT. |
| Pubmed ID | 27584792 |
| Year | 2016 |
| Title | Epstein-Barr virus-encoded miR-BART6-3p inhibits cancer cell metastasis and invasion by targeting long non-coding RNA LOC553103. |
External Links
| Links for LOC553103 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |