Basic Information
| LncRNA/CircRNA Name | LOC730101 |
| Synonyms | NA |
| Region | GRCh38_6:52664401-52669153 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc. |
| Sample | NSCLC tissue, cell lines (A549, H522, H2122) |
| Expression Pattern | up-regulated |
| Function Description | LOC730101 enhances the activity of Wnt/b-catenin signaling to promote the progression of cell cycle and ultimate promotes cell proliferation and growth. LOC730101 may be a potential therapeutic target in NSCLC. |
| Pubmed ID | 28943432 |
| Year | 2017 |
| Title | Highly expressed lncRNA LOC730101 promotes lung cancer cell growth through Wnt canonical pathway |
External Links
| Links for LOC730101 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |