Basic Information
| LncRNA/CircRNA Name | LOC90784 |
| Synonyms | NA |
| Region | GRCh38_2:86020216-86023868 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot |
| Sample | cell lines (HepG2, SMMC7721, Bel-7404, PLiver Cancer /PRF/5), liver cancer tissue |
| Expression Pattern | up-regulated |
| Function Description | These results indicated that LOC90784 upregulation may be a critical oncogene and potential new biomarker in HCC. LOC90784 overexpression was associated with poor clinical features in the two cohorts and poor overall survival rates in HCC patients with clear resection margins (R0) in cohort 2. |
| Pubmed ID | 28651931 |
| Year | 2017 |
| Title | Upregulated long non-coding RNA LOC90784 promotes cell proliferation and invasion and is associated with poor clinical features in HCC. |
External Links
| Links for LOC90784 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |