Basic Information
| LncRNA/CircRNA Name | LOXL1-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:73908071-73928248 |
| Ensemble | ENSG00000261801 |
| Refseq | NR_040066 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | LUAD tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Our present study suggested that LOXL1??S1 expression was considerably increased in LUAD tissues and cells.MYBL2 was discovered to interact with LOXL1??S1 promoter, indicating a positive feedback loop of LOXL1-AS1/miR-423-5p/MYBL2 in LUAD. |
| Pubmed ID | 31758653 |
| Year | 2019 |
| Title | LncRNA LOXL1-AS1 regulates the tumorigenesis and development of lung adenocarcinoma through sponging miR-423-5p and targeting MYBL2 |
External Links
| Links for LOXL1-AS1 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |