Basic Information
| LncRNA/CircRNA Name | LSAMP-AS1 |
| Synonyms | NA |
| Region | GRCh38_3:116360024-116370090 |
| Ensemble | ENSG00000240922 |
| Refseq | NR_109998 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | RT-qPCR, Western blot |
| Sample | PCa tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | LSAMP-AS1 was poorly expressed in PCa tissues and cells.LSAMP-AS1 up-regulates the DCN gene by competitively binding to miR-183-5p, thus inhibiting EMT, proliferation, migration and invasion of PCa cells. |
| Pubmed ID | 31727599 |
| Year | 2019 |
| Title | LSAMP-AS1 binds to microRNA-183-5p to suppress the progression of prostate cancer by up-regulating the tumor suppressor DCN |
External Links
| Links for LSAMP-AS1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |