Basic Information
| LncRNA/CircRNA Name | LUCAT1 |
| Synonyms | NA |
| Region | GRCh38_5:91303029-91314402 |
| Ensemble | ENSG00000248323 |
| Refseq | NR_103548 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | RT-qPCR |
| Sample | ovarian cancer cell lines (CaoV-3, SK-OV-3 and HO-8910) |
| Expression Pattern | up-regulated |
| Function Description | The cell proliferation rate in SK-OV-3 cells with lncRNA LUCAT1 knockdown was remarkably lower in comparison to that in control group.miR-199a-5p overexpression significantly decreased the expression level of lncRNA LUCAT1.LncRNA LUCAT1 is overexpressed in ovarian cancer cells, which may target miR-199a-5p to exert its effects on driving the malignant development of ovarian cancer. |
| Pubmed ID | 32141534 |
| Year | 2020 |
| Title | LncRNA LUCAT1 promotes proliferation of ovarian cancer cells by regulating miR-199a-5p expression |
External Links
| Links for LUCAT1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |