Basic Information
| LncRNA/CircRNA Name | MACC1-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:20141916-20153531 |
| Ensemble | ENSG00000228598 |
| Refseq | NR_046756 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, Luciferase reporter assay |
| Sample | GC tissues,cell lines( AGS,MKN45 ) |
| Expression Pattern | up-regulated |
| Function Description | We previously reported that MACC1-AS1 is overexpressed in GC tissues and facilitates metabolic plasticity through antioxidant production, resulting in a lower ROS load under metabolic stress |
| Pubmed ID | 30742067 |
| Year | 2019 |
| Title | MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer. |
External Links
| Links for MACC1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |