Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853 |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial stromal sarcoma |
| ICD-0-3 | C54 |
| Methods | qPCR, ISH etc. |
| Sample | ESS tissues |
| Expression Pattern | up-regulated |
| Function Description | We detected the metastasis-associated lung adenocarcinoma transcript 1 (MALAT-1) gene as one of the major genes upregulated in ESS. These results indicated that endometrial stromal cells have different phenotypic characteristics between proliferative and secretory phases and the tumor cells of ESS have the phenotypic character of endometrial stromal cells in the proliferative phase. |
| Pubmed ID | 16441420 |
| Year | 2006 |
| Title | Phenotypic characterization of endometrial stromal sarcoma of the uterus. |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for endometrial stromal sarcoma | OMIM COSMIC |