Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853 |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy0 | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR etc. |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | The increased expression of MALAT1 in HCC tissue may represent a good prognostic biomarker for curatively resected HCC. Terefore, in combination with other tumor prognostic factors, the determination of the expression levels of these lncRNAs may lead to a more accurate prediction of HCC prognosis.The increase in the expression levels of MALAT1 in HCC tissues was signifcantly correlated with better overall survival. |
| Pubmed ID | 29170515 |
| Year | 2017 |
| Title | Prognostic Value of Long NonCoding RNA HULC and MALAT1 Following the Curative Resection of Hepatocellular Carcinoma. |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |