Basic Information
| LncRNA/CircRNA Name | MALAT2 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | MALAT2 was frequently over-expressed in cancer tissues and this over-expression was found to significantly correlate with lymph node metastasis and tumor stage.The expression of MALAT2 is upregulated in GC tissues, and a higher expression level of MALAT2 might serve as a negative prognostic marker in stage II/III GC patients which implies the potential application of MALAT2 in the therapeutic treatment of GC. |
| Pubmed ID | 25721209 |
| Year | 2015 |
| Title | MALAT2-activated long noncoding RNA indicates a biomarker of poor prognosis in gastric cancer. |
External Links
| Links for MALAT2 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |