Basic Information
| LncRNA/CircRNA Name | MANCR |
| Synonyms | NA |
| Region | GRCh38_10:4650185-4678154 |
| Ensemble | ENSG00000231298 |
| Refseq | NR_024475 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, RNA-seq etc |
| Sample | cell lines(FGC) |
| Expression Pattern | down-regulated |
| Function Description | Furthermore, RNA sequencing analysis revealed that expression of the genes involved in migration and invasion was altered by MANCR knockdown. In summary, our data demonstrate that MANCR plays a critical role in migration and invasion of PC3 cells. |
| Pubmed ID | 32199616 |
| Year | 2020 |
| Title | Long Non-Coding RNA MANCR Is a Target of BET Bromodomain Protein BRD4 and Plays a Critical Role in Cellular Migration and Invasion Abilities of Prostate Cancer |
External Links
| Links for MANCR | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |