Basic Information
LncRNA/CircRNA Name | MANCR |
Synonyms | NA |
Region | GRCh38_10:4650185-4678154 |
Ensemble | ENSG00000231298 |
Refseq | NR_024475 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR, Western blot etc. |
Sample | HCC tissues,cell line(SNU-398,SNU-182) |
Expression Pattern | up-regulated |
Function Description | MANCR is upregulated in HCC and predicted survival.MANCR overexpression leads to downregulation of miR-122a in HCC cells. |
Pubmed ID | 31788100 |
Year | 2019 |
Title | Mitotically-associated Long Non-Coding RNA Promotes Cancer Cell Proliferation in Hepatocellular Carcinoma by Downregulating miR-122a |
External Links
Links for MANCR | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |