Basic Information
| LncRNA/CircRNA Name | MATN1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:30718504-30726827 |
| Ensemble | ENSG00000186056 |
| Refseq | NR_034182 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, RIP |
| Sample | GBM tissues |
| Expression Pattern | down-regulated |
| Function Description | Upregulation of the lncRNA MATN1-AS1 inhibited GBM cell proliferation and invasion through inhibition of RELA via E2F6 and suppression of the MAPK signaling pathway. |
| Pubmed ID | 32042800 |
| Year | 2019 |
| Title | LncRNA MATN1-AS1 prevents glioblastoma cell from proliferation and invasion via RELA regulation and MAPK signaling pathway |
External Links
| Links for MATN1-AS1 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |