Basic Information
| LncRNA/CircRNA Name | MBNL1-AS1 |
| Synonyms | NA |
| Region | GRCh38_3:152262616-152269555 |
| Ensemble | ENSG00000229619 |
| Refseq | NR_027037 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, RIP |
| Sample | NSCLC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | MBNL1-AS1 was able to regulate miR-135a-5p expression negatively. MBNL1-AS1 remarkably restrained tumorigenic ability of NSCLC through sponging miR-135a-5p in vivo. |
| Pubmed ID | 32092823 |
| Year | 2020 |
| Title | Down-regulation of MBNL1-AS1 contributes to tumorigenesis of NSCLC via sponging miR-135a-5p |
External Links
| Links for MBNL1-AS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |