Basic Information
| LncRNA/CircRNA Name | BANCR |
| Synonyms | BANCR, LINC00586 |
| Region | GRCh38_9:69296682-69311111 |
| Ensemble | ENSG00000278910 |
| Refseq | NR_047671 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc. |
| Sample | lung cancer tissues, cell lines (NCI-H1688, NCI-H446) |
| Expression Pattern | down-regulated |
| Function Description | The results showed that BANCR levels were downregulated in LC cells. When BANCR expression was improved by tranfetcion with pcDNA-BANCR vetcor, tumor growth was suppressed.Vise versa, when BANCR was knockdown by si-BANCR, cell proliferation and migration of LC were remarkably promoted. We further found that MAPK pathways were involved in the BANCR-mediated cell proliferation and migration of LC. |
| Pubmed ID | 25661343 |
| Year | 2015 |
| Title | Long non-coding RNA BANCR promotes proliferation and migration of lung carcinoma via MAPK pathways. |
External Links
| Links for BANCR | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |