Basic Information
| LncRNA/CircRNA Name | MHENCR |
| Synonyms | NA |
| Region | GRCh38_20:63627227-63628824 |
| Ensemble | ENSG00000232442 |
| Refseq | NR_132417 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RIP |
| Sample | malignant melanoma tissues, cell lines (A375 and SK-MEL-2) |
| Expression Pattern | up-regulated |
| Function Description | In this study, we identified a novel lncRNA MHENCR which was upregulated in melanoma tissues and further upregulated in metastatic melanoma. Increased expression of MHENCR indicted poor survival of melanoma patients. |
| Pubmed ID | 28123636 |
| Year | 2017 |
| Title | Long noncoding RNA MHENCR promotes melanoma progression via regulating miR-425/489-mediated PI3K-Akt pathway |
External Links
| Links for MHENCR | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |