Basic Information
| LncRNA/CircRNA Name | MIA-RAB4B |
| Synonyms | MIA-RAB4B |
| Region | GRCh38_19:40771648-40796943 |
| Ensemble | ENSG00000268975 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Microsatellite instability assay etc. |
| Sample | Peripheral lymphocyte and tissues |
| Expression Pattern | down-regulated |
| Function Description | Although the expressions of MIA and MIA-RAB4B were consistently down-regulated in the polyps of 421 compared to the matched mucosa, the expressions of these genes were one to five fold up-regulated in the polyps of 344. |
| Pubmed ID | 28306719 |
| Year | 2017 |
| Title | Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients. |
External Links
| Links for MIA-RAB4B | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |