Basic Information
| LncRNA/CircRNA Name | MIR17HG |
| Synonyms | NA |
| Region | GRCh38_13:91347820-91354579 |
| Ensemble | ENSG00000215417 |
| Refseq | NR_027349 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | PCR, Western blot, RIP |
| Sample | OS tissue,cell lines (Saos-2, U2-OS, 143 B, MG63) |
| Expression Pattern | up-regulated |
| Function Description | MIR17HG displays the tumor-promotive role in the progression of OS through SP1/MIR17HG/miR-130a-3p/SP1 feedback loop. Our findings might help us to offer novel therapeutic strategies for OS. |
| Pubmed ID | 31706574 |
| Year | 2019 |
| Title | Positive feedback loop SP1/MIR17HG/miR-130a-3p promotes osteosarcoma proliferation and cisplatin resistance |
External Links
| Links for MIR17HG | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |