Basic Information
| LncRNA/CircRNA Name | MIR205HG |
| Synonyms | ENSG00000230937 |
| Region | GRCh38_1:209428820-209432838 |
| Ensemble | ENSG00000230937 |
| Refseq | NR_145433 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | RNA-seq |
| Sample | cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Lastly, we experimentally demonstrate that 2 lncRNAs, EGFR-AS1 and MIR205HG, are functionally relevant predictors of anti-epidermal growth factor receptor (EGFR) drug response.Without considering EGFR functional events, both EGFR-AS1 and MIR205HG expression levels were higher in the cells sensitive to gefitinib or erlotinib |
| Pubmed ID | 31548386 |
| Year | 2019 |
| Title | Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes. |
External Links
| Links for MIR205HG | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |