Basic Information
| LncRNA/CircRNA Name | MIR22HG |
| Synonyms | NA |
| Region | GRCh38_17:1711493-1717174 |
| Ensemble | ENSG00000186594 |
| Refseq | NR_028502 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngocarcinoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, Western blot |
| Sample | laryngocarcinoma cell lines (UM-SCC-10B,SNU899 and SNU46) |
| Expression Pattern | down-regulated |
| Function Description | E2F6-induced down-regulation of MIR22HG promotes laryngocarcinoma progression through miR-5000-3p/FBXW7 axis. |
| Pubmed ID | 32094308 |
| Year | 2020 |
| Title | E2F6-mediated down-regulation of MIR22HG facilitates the progression of laryngocarcinoma by targeting miR-5000-3p/FBXW7 axis |
External Links
| Links for MIR22HG | GenBank HGNC NONCODE |
| Links for laryngocarcinoma | OMIM COSMIC |