Basic Information
| LncRNA/CircRNA Name | MIR4435-2HG |
| Synonyms | NA |
| Region | GRCh38_2:111036776-111523376 |
| Ensemble | ENSG00000172965 |
| Refseq | NR_015395 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | RT-qPCR, Western blot |
| Sample | OSCC cell lines,blood |
| Expression Pattern | up-regulated |
| Function Description | The results showed that levels of MIR4435-2HG and TGF-?1 in plasma were upregulated in OSCC.MIR4435-2HG regulates the behaviors of OSCC cells by promoting the expression of TGF-?1. |
| Pubmed ID | 32016787 |
| Year | 2020 |
| Title | MIR4435-2HG regulates cancer cell behaviors in?oral squamous cell carcinoma cell growth by?upregulating TGF-?1 |
External Links
| Links for MIR4435-2HG | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |