Basic Information
| LncRNA/CircRNA Name | MIR503HG |
| Synonyms | NA |
| Region | GRCh38_X:134543337-134546632 |
| Ensemble | ENSG00000223749 |
| Refseq | NR_024607 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | NSCLC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | the expression of MIR503HG was significantly upregulated in NSCLC tissues compared with adjacent tissues. knockdown of MIR503HG suppressed proliferation and promoted apoptosis of NSCLC cells through regulating miR-489-3p and miR-625-5p. |
| Pubmed ID | 31983569 |
| Year | 2020 |
| Title | Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p |
External Links
| Links for MIR503HG | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |