Basic Information
| LncRNA/CircRNA Name | MIR503HG |
| Synonyms | NA |
| Region | GRCh38_X:134543337-134546632 |
| Ensemble | ENSG00000223749 |
| Refseq | NR_024607 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Dual luciferase assay, qRT-PCR |
| Sample | Ovarian biopsy ,OC cell lines, UWB1.289 and A2780 |
| Expression Pattern | down-regulated |
| Function Description | miR503HG was downregulated in OC and may suppress OC by increasing the methylation of miR-31-5p gene and sponging mature miR-31-5p.MiR503HG suppressed OC cell invasion and migration through miR-31-5p. |
| Pubmed ID | 31907059 |
| Year | 2020 |
| Title | LncRNA miR503HG Interacts With miR-31-5p Through Multiple Ways to Regulate Cancer Cell Invasion and Migration in Ovarian Cancer |
External Links
| Links for MIR503HG | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |