Basic Information
| LncRNA/CircRNA Name | MIR503HG |
| Synonyms | MIR503HG, H19X, MIR503HG2 |
| Region | GRCh38_X:134543337-134546632 |
| Ensemble | ENSG00000223749 |
| Refseq | NR_024607 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | choriocarcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Cell transfection, Cell cycle assay etc. |
| Sample | placenta tissues, cell line (JEG-3) |
| Expression Pattern | down-regulated |
| Function Description | MIR503HG and LINC00629 were lower expressed in JEG-3 cell line than in normal placenta tissues. We found that the overexpression of both lincRNAs could inhibit migration and invasion in JEG-3 choriocarcinoma cell line.Furthermore, using the normal tissue panel, we observed a significant positive correlation between MIR503HG and LINC00629 lincRNAs, and also between both lincRNAs and the neighboring miRNAs: miR-424, miR450a, miR-450b-5p, miR-542-3p and miR-503 |
| Pubmed ID | 27023770 |
| Year | 2016 |
| Title | Placenta-Enriched LincRNAs MIR503HG and LINC00629 Decrease Migration and Invasion Potential of JEG-3 Cell Line. |
External Links
| Links for MIR503HG | GenBank HGNC NONCODE |
| Links for choriocarcinoma | OMIM COSMIC |