Basic Information
| LncRNA/CircRNA Name | MIR7-3HG |
| Synonyms | NA |
| Region | GRCh38_19:4769140-4772533 |
| Ensemble | ENSG00000176840 |
| Refseq | NR_027148 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Retinoblastoma |
| ICD-0-3 | C69.2 |
| Methods | qRT-PCR, Western blot |
| Sample | RB tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | MIR7-3HG functioned as a ceRNA to up-regulate PEG10 expression via sponging miR-27a-3p to promote the proliferation of Rb cells and suppress the apoptosis of Rb cells |
| Pubmed ID | 32035086 |
| Year | 2020 |
| Title | LncRNA MIR7-3HG executes a positive role in retinoblastoma progression via modulating miR-27a-3p/PEG10 axis |
External Links
| Links for MIR7-3HG | GenBank HGNC NONCODE |
| Links for Retinoblastoma | OMIM COSMIC |