Basic Information
| LncRNA/CircRNA Name | BBOX1-AS1 |
| Synonyms | NA |
| Region | GRCh38_11:27047186-27220113 |
| Ensemble | ENSG00000254560 |
| Refseq | NR_125766 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western bolt |
| Sample | CRC cell lines |
| Expression Pattern | up-regulated |
| Function Description | BBOX1-AS1 is overexpressed in CRC cell lines, and BBOX1-AS1 knockdown enhances cell proliferation, migration and invasion while reducing cell apoptosis. |
| Pubmed ID | 31984680 |
| Year | 2020 |
| Title | BBOX1-AS1 contributes to colorectal cancer progression by sponging hsa-miR-361-3p and targeting SH2B1 |
External Links
| Links for BBOX1-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |