Basic Information
| LncRNA/CircRNA Name | MVIH |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | nedaplatin,Cisplatin | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot analysis |
| Sample | cell lines A549 and H1650 |
| Expression Pattern | up-regulated |
| Function Description | LncRNA MVIH is upregulated in drug resistant NSCLC cells. Nedaplatin can reduce the expression of MVIH and reverse EMT process, thus reversing the drug resistance of cisplatin in non-small cell lung cancer cells. |
| Pubmed ID | 31942179 |
| Year | 2020 |
| Title | Nedaplatin Reduces Multidrug Resistance of Non-Small Cell Lung Cancer by Downregulating the Expression of Long Non-Coding RNA MVIH |
External Links
| Links for MVIH | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |