Basic Information
| LncRNA/CircRNA Name | BC008363 |
| Synonyms | LINC00491 |
| Region | GRCh38_5:102609156-102671559 |
| Ensemble | ENSG00000250682 |
| Refseq | NR_103753 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic ductal adenocarcinoma |
| ICD-0-3 | C25.3 |
| Methods | Microarray, qPCR etc. |
| Sample | PDAC tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that the expression level of lncRNA BC008363 was significantly lower (23-fold) in PDAC tissues compared to corresponding nontumor pancreatic tissues, and patients with high levels of lncRNA BC008363 expression had significantly better survival rates than those with low levels of lncRNA BC008363 expression. lncRNA BC008363 may be a novel biomarker for the prognosis of pancreatic cancer. |
| Pubmed ID | 25200694 |
| Year | 2014 |
| Title | Long non-coding RNAs expressed in pancreatic ductal adenocarcinoma and lncRNA BC008363 an independent prognostic factor in PDAC. |
External Links
| Links for BC008363 | GenBank HGNC NONCODE |
| Links for pancreatic ductal adenocarcinoma | OMIM COSMIC |