Basic Information
| LncRNA/CircRNA Name | MYOSLID |
| Synonyms | NA |
| Region | GRCh38_2:207239650-207245887 |
| Ensemble | ENSG00000229647 |
| Refseq | NR_146555 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Dual Luciferase Reporter Assay |
| Sample | OS samples,OS cell lines and the hFOB1.19 cells |
| Expression Pattern | up-regulated |
| Function Description | The expression of MYOSLID was upregulated in OS tissues and cell lines. MYOSLID overexpression predicted poor prognosis in OS patients. MYOSLID knockdown suppressed proliferation, migration and invasion of OS cells. MYOSLID was the sponge for miR-1286 and inhibited its expression while miR-1286 targeted RAB13 directly. MYOSLID promoted RAB13 expression via sponging miR-1286. |
| Pubmed ID | 31849524 |
| Year | 2019 |
| Title | A Novel lncRNA MYOSLID/miR-1286/RAB13 Axis Plays a Critical Role in Osteosarcoma Progression |
External Links
| Links for MYOSLID | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |