Basic Information
| LncRNA/CircRNA Name | n689 |
| Synonyms | TERC, DKCA1, PFBMFT2, SCARNA19, TR, TRC3, hTR |
| Region | NA |
| Ensemble | ENSG00000270141 |
| Refseq | NR_001566 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR etc. |
| Sample | NPC tissues, cell lines (CNE-2 and 6-10B) |
| Expression Pattern | up-regulated |
| Function Description | To confirm the consistency of the known and novel lncRNA expression profiles, the top five upregulated and downregulated lncRNAs in both the known and novel lncRNAs were identified. Our qRT-PCR assays verified that 7 of 10 known lncRNAs exhibited a significant differential expression with the same trend observed in the deep sequencing prediction, including the upregulated lncRNAs n333177, n689, and n375997 and the downregulated lncRNAs n376834, n381831, n370764, and n341810. |
| Pubmed ID | 27599611 |
| Year | 2016 |
| Title | Genome-wide analyses of long noncoding RNA expression profiles correlated with radioresistance in nasopharyngeal carcinoma via next-generation deep sequencing. |
External Links
| Links for n689 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |