Basic Information
| LncRNA/CircRNA Name | NAG7 |
| Synonyms | LINC00312, ERR-10, ERR10, LMCD1DN, LOH3CR2A, NAG-7, NAG7, NCRNA00312 |
| Region | NA |
| Ensemble | NA |
| Refseq | NR_024065 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | Microarray, ISH etc. |
| Sample | NPC, TMA tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that LINC00312 was significantly down-regulated in NPC tissues compared with non-cancerous nasopharyngeal epithelium tissues. Positive expression of LINC00312 was negatively correlated with tumor size but positively correlated with lymph node metastasis. A receiver operating characteristic (ROC) analysis revealed that LINC00312 expression could distinguish non-cancerous patients from NPC patients. These observations indicated that LINC00312 could represent a potential biomarker for metastasis, progression and prognosis in NPC. |
| Pubmed ID | 23529758 |
| Year | 2013 |
| Title | Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma. |
External Links
| Links for NAG7 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |