Basic Information
| LncRNA/CircRNA Name | NBAT1 |
| Synonyms | NBAT1, CASC14, NBAT-1 |
| Region | GRCh38_6:22134957-22147193 |
| Ensemble | ENSG00000260455 |
| Refseq | NR_034143 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot etc. |
| Sample | ovarian cancer tissues, cell lines (A2780, TOV112D, HO-8910, OVCAR-3, and SKOV3) |
| Expression Pattern | down-regulated |
| Function Description | We found that lncRNA NBAT-1 was obviously downregulated in OC tissue compared to normal ovarian tissue (P<0.001) which was free of OC, and the detected levels of NBAT-1 were associated with the International Federation of Gynecology and Obstetrics stage and tumor size guidelines. Moreover, it has been shown that lower levels of NBAT-1 predict poor outcomes of OC. |
| Pubmed ID | 28435289 |
| Year | 2017 |
| Title | Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer |
External Links
| Links for NBAT1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |