Basic Information
| LncRNA/CircRNA Name | nc886 |
| Synonyms | VTRNA2-1, CBL-3, CBL3, MIR886, MIRN886, VTRNA2, hsa-mir-886, hvg-5, nc886, svtRNA2-1a |
| Region | GRCh38_5:136080470-136080597 |
| Ensemble | ENSG00000270123 |
| Refseq | NR_030583 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RNA-seq, qPCR etc. |
| Sample | gastric cancer tissues, gastric cell lines |
| Expression Pattern | down-regulated |
| Function Description | Our real-time RT-PCR data (Fig 1A) indicated that the expression level of nc886 was lower in a subpopulation of tumor tissues than in normal tissues. nc886 inhibits cell proliferation when ectopically expressed in gastric cancer cells. |
| Pubmed ID | 25003254 |
| Year | 2014 |
| Title | nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer. |
External Links
| Links for nc886 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |