Basic Information
| LncRNA/CircRNA Name | NEAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65422774-65445540 |
| Ensemble | ENSG00000245532 |
| Refseq | NR_028272 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qRT-PCR, Western blot |
| Sample | colon cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | NEAT1 upregulate IGF2 expression through absorbing miR-185-5p to enhances the migration and invasion of colon cancer cells. |
| Pubmed ID | 32077635 |
| Year | 2020 |
| Title | LncRNA NEAT1/miR-185-5p/IGF2 axis regulates the invasion and migration of colon cancer |
External Links
| Links for NEAT1 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |